RESUMO
Abstract Lupus tumidus is considered a rare subtype of chronic cutaneous lupus erythematosus, characterized by erythema and bright urticarial erythematous-violaceous lesions that leave no scars after regression. Histopathology reveals perivascular and periannexal lymphohistiocytic infiltrates in the papillary and reticular dermis and interstitial mucin deposition. Treatment is based on photoprotection, topical corticosteroids and antimalarials. We report two cases of lupus tumidus, which deserve attention for their low frequency in the literature, in addition to their relevance as a differential diagnosis among dermatologic disorders.
Assuntos
Humanos , Feminino , Pessoa de Meia-Idade , Pele/patologia , Lúpus Eritematoso Cutâneo/patologia , Biópsia , Lúpus Eritematoso Cutâneo/tratamento farmacológico , Prednisona/uso terapêutico , Cloroquina/uso terapêutico , Resultado do Tratamento , Glucocorticoides/uso terapêutico , Mucinas , Antimaláricos/uso terapêuticoRESUMO
Abstract Porokeratosis is a skin disorder clinically characterized by annular plaques with keratotic borders resembling the Great Wall of China and histopathologically by cornoid lamellae. The disease has several clinical variants. Porokeratosis ptychotropica, which has recently become part of these variants, is quite rare and little known. The entity is characterized by verrucous plaques – which may resemble a psoriasis plaque – that affect the regions of the buttocks, most commonly the gluteal cleft, with or without extremity involvement. Itching is often present. We report a rare case of porokeratosis ptychotropica and highlight its unusual manifestation (single plaque), the first case reported in the Brazilian literature.
Assuntos
Humanos , Masculino , Adulto Jovem , Pele/patologia , Poroceratose/patologia , Prurido , Biópsia , Brasil , Nádegas/patologia , Eritema/patologiaRESUMO
Abstract Plasmoacanthoma is an extremely rare verrucous tumor located on periorificial regions characterized by dense dermal plasmacytic infiltrates. Some authors classify it as a form of reactive plasma cell proliferation which represents a heterogeneous spectrum of mucocutaneous disorders. These plasma cell proliferations have been considered to be a benign immunologic inflammatory reaction to known or unknown stimuli. However, the etiology of plasmoacanthoma remains highly speculative. We report the case of a 40-year-old woman who presented with a lobulated warty lesion affecting the lower lip. Biopsy from the lesion was compatible with plasmoacanthoma, which remains an underreported disease in the dermatology literature.
Assuntos
Humanos , Feminino , Adulto , Neoplasias Cutâneas/patologia , Neoplasias Labiais/patologia , Acantoma/patologia , Mucosa Bucal/patologia , Plasmócitos/patologia , Biópsia , Imuno-Histoquímica , Derme/patologia , Proliferação de Células , Lábio/patologiaRESUMO
Cutaneous metastasis is a rare manifestation of visceral malignancies that indicates primarily advanced disease. Due to its low incidence and similarity to other cutaneous lesions, it is not uncommon to have a delayed diagnosis and a shortened prognosis. We describe the case of a patient who presented with a cutaneous nodule in the sternal region as a first sign of malignancy.
Assuntos
Adenocarcinoma/secundário , Neoplasias Gastrointestinais , Neoplasias Primárias Desconhecidas/patologia , Neoplasias Cutâneas/secundário , Idoso de 80 Anos ou mais , Biópsia , Evolução Fatal , Feminino , HumanosRESUMO
Glomus tumors originate from modified perivascular muscle cells. The most common form is the solitary one. The multiple form may be associated with dominant genetic inheritance. We report a case of a patient with hemangiomatous lesions on the calcaneus and wrist since birth. In 6 years, there was progression of lesions throughout the body. Multiple glomangiomas are asymptomatic and more common in childhood. They can be confused with other vascular malformations. Histopathological diagnosis is essential. The case shows a type 2 segmental manifestation that can be explained by genetic mutation leading to the loss of heterozygosity. As the child grows, the lesions may disseminate due to mutation in distant parts of the skin. Literature shows few reports. The treatment is conservative.
Assuntos
Tumor Glômico/patologia , Paraganglioma Extrassuprarrenal/patologia , Neoplasias Cutâneas/patologia , Tumor Glômico/genética , Humanos , Masculino , Mutação , Paraganglioma Extrassuprarrenal/genética , Pele/patologia , Neoplasias Cutâneas/genética , Adulto JovemRESUMO
AbstractCutaneous metastasis is a rare manifestation of visceral malignancies that indicates primarily advanced disease. Due to its low incidence and similarity to other cutaneous lesions, it is not uncommon to have a delayed diagnosis and a shortened prognosis. We describe the case of a patient who presented with a cutaneous nodule in the sternal region as a first sign of malignancy.
Assuntos
Idoso de 80 Anos ou mais , Feminino , Humanos , Adenocarcinoma/secundário , Neoplasias Gastrointestinais , Neoplasias Primárias Desconhecidas/patologia , Neoplasias Cutâneas/secundário , Biópsia , Evolução FatalRESUMO
Glomus tumors originate from modified perivascular muscle cells. The most common form is the solitary one. The multiple form may be associated with dominant genetic inheritance. We report a case of a patient with hemangiomatous lesions on the calcaneus and wrist since birth. In 6 years, there was progression of lesions throughout the body. Multiple glomangiomas are asymptomatic and more common in childhood. They can be confused with other vascular malformations. Histopathological diagnosis is essential. The case shows a type 2 segmental manifestation that can be explained by genetic mutation leading to the loss of heterozygosity. As the child grows, the lesions may disseminate due to mutation in distant parts of the skin. Literature shows few reports. The treatment is conservative.
.Assuntos
Humanos , Masculino , Adulto Jovem , Tumor Glômico/patologia , Paraganglioma Extrassuprarrenal/patologia , Neoplasias Cutâneas/patologia , Tumor Glômico/genética , Mutação , Paraganglioma Extrassuprarrenal/genética , Neoplasias Cutâneas/genética , Pele/patologiaRESUMO
Tumor of the follicular infundibulum is a rare benign cutaneous adnexal neoplasm with variable clinical presentation. In most cases the diagnosis is made with the help of histopathology, due to lack of a characteristic clinical presentation. The most common form is a solitary lesion, but it can be multiple or eruptive, then called infundibulomatose. This case report illustrates a patient with multiple lesions of tumor of the follicular infundibulum with bizarre aspect and atypical location.
Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias de Anexos e de Apêndices Cutâneos/patologia , Neoplasias Cutâneas/patologia , Biópsia , Pele/patologiaRESUMO
Tumor of the follicular infundibulum is a rare benign cutaneous adnexal neoplasm with variable clinical presentation. In most cases the diagnosis is made with the help of histopathology, due to lack of a characteristic clinical presentation. The most common form is a solitary lesion, but it can be multiple or eruptive, then called infundibulomatose. This case report illustrates a patient with multiple lesions of tumor of the follicular infundibulum with bizarre aspect and atypical location.
Assuntos
Neoplasias de Anexos e de Apêndices Cutâneos/patologia , Neoplasias Cutâneas/patologia , Biópsia , Humanos , Masculino , Pessoa de Meia-Idade , Pele/patologiaRESUMO
Sarcoidosis is a multisystem granulomatous disease of unknown cause. The osteoarticular involvement in sarcoidosis is rare and is often associated with cutaneous and long-standing chronic multisystem disease. More common in black women, osseous sarcoidosis is difficult to diagnose, with an incidence of 3 to 13%. The most characteristic radiological clinical picture evidences rounded, well-defined cysts, with no periosteal reaction and without peripheral sclerosis. The small bones of hands and feet are the most frequently involved sites. This report aims to demonstrate a rare case of osteoarticular sarcoidosis with characteristic clinical presentation, and highlight the importance of detecting osteoarticular involvement in this pathology.
Assuntos
Doença Granulomatosa Crônica/patologia , Doenças Musculoesqueléticas/patologia , Sarcoidose/patologia , Dermatopatias/patologia , Idoso de 80 Anos ou mais , Feminino , Doença Granulomatosa Crônica/diagnóstico por imagem , Ossos da Mão/diagnóstico por imagem , Ossos da Mão/patologia , Humanos , Doenças Musculoesqueléticas/diagnóstico por imagem , Radiografia , Sarcoidose/diagnóstico por imagem , Dermatopatias/diagnóstico por imagem , Telangiectasia/patologiaRESUMO
Sarcoidosis is a multisystem granulomatous disease of unknown cause. The osteoarticular involvement in sarcoidosis is rare and is often associated with cutaneous and long-standing chronic multisystem disease. More common in black women, osseous sarcoidosis is difficult to diagnose, with an incidence of 3 to 13%. The most characteristic radiological clinical picture evidences rounded, well-defined cysts, with no periosteal reaction and without peripheral sclerosis. The small bones of hands and feet are the most frequently involved sites. This report aims to demonstrate a rare case of osteoarticular sarcoidosis with characteristic clinical presentation, and highlight the importance of detecting osteoarticular involvement in this pathology.
Assuntos
Idoso de 80 Anos ou mais , Feminino , Humanos , Doença Granulomatosa Crônica/patologia , Doenças Musculoesqueléticas/patologia , Sarcoidose/patologia , Dermatopatias/patologia , Doença Granulomatosa Crônica , Ossos da Mão/patologia , Ossos da Mão , Doenças Musculoesqueléticas , Sarcoidose , Dermatopatias , Telangiectasia/patologiaRESUMO
Ewing sarcoma is a primitive neuroectodermal tumor rarely occurs in the skin and sobcutaneous tissues. Generally Ewing's sarcoma is a primary bone tumor, but when present in soft tissues it characterizes an extremely uncommon clinical picture. It usually involves the deep subcutaneous tissue or muscles, and more rarely occurs like a primary skin cancer. Most patients are white, women, and in the second decade of life. The clinical features are a superficial mass, in average measuring 2-3 cm, of soft consistency, freely mobile and sometimes painful. The more affected locations are upper and lower extremities, trunk, head, neck or multiple lesions. The presence of metastases is very rare.
Assuntos
Sarcoma de Ewing/patologia , Neoplasias Cutâneas/patologia , Tela Subcutânea/patologia , Adulto , Diagnóstico Diferencial , Feminino , HumanosRESUMO
Ewing sarcoma is a primitive neuroectodermal tumor rarely occurs in the skin and sobcutaneous tissues. Generally Ewing's sarcoma is a primary bone tumor, but when present in soft tissues it characterizes an extremely uncommon clinical picture. It usually involves the deep subcutaneous tissue or muscles, and more rarely occurs like a primary skin cancer. Most patients are white, women, and in the second decade of life. The clinical features are a superficial mass, in average measuring 2-3 cm, of soft consistency, freely mobile and sometimes painful. The more affected locations are upper and lower extremities, trunk, head, neck or multiple lesions. The presence of metastases is very rare.
Assuntos
Adulto , Feminino , Humanos , Sarcoma de Ewing/patologia , Neoplasias Cutâneas/patologia , Tela Subcutânea/patologia , Diagnóstico DiferencialRESUMO
Este estudo clínico foi realizado com Filtrum FPS 50 Alta Proteção em voluntários saudáveis. Realizou-se avaliação sensorial...
Assuntos
Humanos , Feminino , Pessoa de Meia-Idade , Filtros UltravioletasRESUMO
Os neuromas encapsulados em paliçada são tumores neurais solitários da pele caracterizados pela presença de feixes compactos e paralelos de fascículos de células de Schwann. Apresenta-se um caso desse tumor, confirmado por exame anatomopatológico, em paciente do sexo feminino, de 55 anos, que relatou mácula hipocrômica de crescimento que evoluiu para pápula de superfície lisa e em domo, com telangiectasias, simulando carcinoma basocelular. Ter conhecimento dessa entidade é importante para a realização de diagnósticos diferenciais com outras lesões, em especial com o CBC, tumores de apêndice cutâneo, nevos e cistos epidérmicos.
Palisaded encapsulated neuromas are solitary neural skin tumors characterized by the presence of compact and parallel bundles of Schwann cell fascicles. The present article reports a case of this type of tumor, which was confirmed by anatomic pathological examination of a 55-year-old female patient who reported hypochromic macula growth, which had evolved into a smooth domed superficial papule with telangiectasias, simulating a basal cell carcinoma. Having knowledge of this entity is crucial in order to carry out differential diagnoses-comparing it to other lesions-especially basal cell carcinomas, skin appendage tumors, nevi, and epidermal cysts.
RESUMO
O Ambiente Interativo de Aprendizagem (AIA) é um modelo educacional que integra recursos de computação gráfica 3D e contextualização, com objetivo de transmitir um conjunto de conhecimentos (ilhas de conhecimento), de forma precisa e ágil, para pessoas que não conhecem o assunto. Utiliza recursos de multimídia apoiados em ambientação contextualizada para motivar os participantes na retenção de conhecimento. Na primeira versão, foram abordados oito assuntos relevantes de dermatologia. O modelo foi implementado no 62º Congresso Brasileiro de Dermatologia e denominado Dermatúnel. Participaram das visitas 3295 pessoas, num período de quatro dias. Os resultados demonstraram alta satisfação dos participantes. Possui grande potencial como ferramenta educacional para formação médica e orientação do público geral para fins de prevenção de doenças.
The Interactive Learning Environment (ILE) is an educational model that integrates features of 3D computer graphics and contextualization, in order to transmit a quantum of knowledge (islands of knowledge), in a precise and agile way, to people who do not know the subject. It is a model that uses multimedia resources supported by a contextualized environment to motivate the participants in the retention of knowledge. In this first release, eight relevant subjects in dermatology were addressed and implemented in the 62nd Brazilian Congress of Dermatology. The model was called Dermatúnel. In a period of four days, 3295 people visited it. The results showed that the participants were highly satisfied. The model has a great potential as an educational tool for medical training and guidance to the general public with the purpose of disease prevention.
Assuntos
Humanos , Recursos Audiovisuais , Educação em Saúde , Telemedicina , Multimídia , Educação a Distância , Prevenção de Doenças , Treinamento por SimulaçãoRESUMO
O Ambiente Interativo de Aprendizagem (AIA) é um modelo educacional que integra recursos de computação gráfica 3D e contextualização, com objetivo de transmitir um conjunto de conhecimentos (ilhas de conhecimento), de forma precisa e ágil, para pessoas que não conhecem o assunto. Utiliza recursos de multimídia apoiados em ambientação contextualizada para motivar os participantes na retenção de conhecimento. Na primeira versão, foram abordados oito assuntos relevantes de dermatologia. O modelo foi implementado no 62º Congresso Brasileiro de Dermatologia e denominado Dermatúnel. Participaram das visitas 3295 pessoas, num período de quatro dias. Os resultados demonstraram alta satisfação dos participantes. Possui grande potencial como ferramenta educacional para formação médica e orientação do público geral para fins de prevenção de doenças.(AU)
Assuntos
Humanos , Educação a Distância , Aprendizagem , Educação em Saúde , TelemedicinaRESUMO
Apresenta informações sobre acne com ilustrações, mostra o que é, como é, como se dá sua formação, quais os tipos, o que causa, onde é encontrada, suas cosequências, anatomia e cuidados com a pele e lista de discussão, história em quadrinhos, e um desafio constituído por 3 conjuntos de 10 perguntas, com 4 alternativas cada. Completando as 3 fases, recebe o direito a participar da Discussão com o Dermatologista.